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Dimethyl sulfoxide CAS:67-68-5

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  • CAS   67-68-5
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Introduction
Product Name: Dimethyl sulfoxide
Synonyms: (CH3)2SO;A 10846;a10846;Decap;Deltan;Demasorb;Demavet;Demeso
CAS: 67-68-5
MF: C2H6OS
MW: 78.13
EINECS: 200-664-3
Product Categories: Pharmaceutical Intermediates;INORGANIC & ORGANIC CHEMICALS;Organics;Analytical Chemistry
Mol File: 67-68-5.mol
Dimethyl sulfoxide Chemical Properties
mp  18.4 °C
bp  189 °C(lit.)
density  1.100 g/mL at 20 °C
vapor density  2.7 (vs air)
vapor pressure  0.42 mm Hg ( 20 °C)
FEMA  3875
refractive index  n20/D1.479(lit.)
Fp  192 °F
storage temp.  Store at RT.
form  liquid (temperature dependent)
color  clear colorless
FreezingPoint  18.4℃
Sensitive  Hygroscopic
Merck  14,3259
BRN  506008
Stability: Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic.
CAS DataBase Reference 67-68-5(CAS DataBase Reference)
NIST Chemistry Reference Dimethyl sulfoxide(67-68-5)
EPA Substance Registry System Methane, sulfinylbis-(67-68-5)

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-37/39-26-36-23
WGK Germany  1
RTECS  PV6210000
3
HS Code  29309070
Hazardous Substances Data 67-68-5(Hazardous Substances Data)

Dimethyl sulfoxide Usage And Synthesis


Application 1. It can be used for the extraction of arene, also as the reaction medium used for resins and dyes, and applied to acrylic polymerization and spinning solvent. 
2. It can be used as an organic solvent, reaction medium and the intermediates of organic synthesis. It is highly versatile. This product has a highly selective extraction capacity, and can be used as the polymerization and condensation solvent of acrylic resin and polysulfone resin, as the polymerization and spinning solvent of polyacrylonitrile and cellulose acetate, as the extraction solvent for separating alkanes and arenes, and as the reaction medium for the arenes, butadiene extraction, acrylic fiber, plastic solvents, organic and synthetic dyes, and pharmaceuticals industries. In the field of medicine, dimethyl sulfoxide has anti-inflammatory and analgesic effect with a strong capability of penetration through the skin, and thus being able to dissolve certain drugs and boost their penetration into the human body to achieve the therapeutic purposes. Taking this carrier property of dimethyl sulfoxide can make it be used as pesticide additives. Add a small amount of dimethyl sulfoxide in some pesticides can facilitate the penetration of pesticides into the plant in order to improve the efficacy. dimethyl sulfoxide can also be used as the dye solvent, dye removing agent, and dye carrier for the synthetic fibers. It can also be used as the absorbent of recycling acetylene and sulfur dioxide and also the modifiers of synthetic fiber, antifreeze agent and the capacitor dielectric, brake oil, and extractant of the rare metals. 
3. It can be used as analytic solvents and fixing agent of gas chromatography as well as the solvent for analyzing UV spectra.
Chemical Properties colourless liquid
Usage DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS).
Usage Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers
Usage Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR.
Usage A polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs.
Usage Suitable for HPLC, spectrophotometry, environmental testing

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